Profound Amnesia after Temporal Lobectomy: An Autoimmune Process Resembling Patient H.M.
نویسندگان
چکیده
منابع مشابه
Profound Amnesia after Temporal Lobectomy: An Autoimmune Process Resembling Patient H.M.?
We describe a patient who developed significant cognitive decline with profound amnesia following non-dominant temporal lobectomy for refractory seizures, in whom the original suspicion of structural pathology was revised following the discovery of clinical and neuropathological markers of inflammation, neuropsychological evidence of bilateral involvement, and high titres of antibodies directed...
متن کاملAmnesia in temporal lobectomy patients: Historical perspective and review
Profound memory loss is a rare but serious complication of temporal-lobe surgery for the relief of medically intractable epilepsy. This paper examines the characteristics of the patients who have been reported to become amnesic following temporal-lobe surgery over the last four decades. The critical role of the hippocampi in memory function are implicated in autopsy studies and MRI investigatio...
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E. P. became profoundly amnesic in 1992 after viral encephalitis, which damaged his medial temporal lobe bilaterally. Because of the rarity of such patients, we have performed a detailed neuroanatomical analysis of E. P.'s lesion using magnetic resonance imaging, and we have assessed his cognitive abilities with a wide range of neuropsychological tests. Finally, we have compared and contrasted ...
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Until recently, it seemed unlikely that any semantic knowledge could be acquired following extensive bilateral damage to the medial temporal lobes (MTL). Although recent studies have demonstrated some semantic learning in amnesic patients, questions remain regarding the limits of this capacity and the extent to which it relies on those patients' residual MTL function. The present study examined...
متن کاملPost-ictal psychosis after right temporal lobectomy.
Of 298 patients who had temporal lobectomies for intractable epilepsy, 4 (1.3%) developed post-ictal psychosis for the first time after surgery. All were males of normal intelligence with no pre-operative psychiatric disorder. Psychosis followed both complex partial and generalised seizures. The psychotic symptoms showed polymorphic features. Right temporal lobectomy may increase the susceptibi...
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ژورنال
عنوان ژورنال: Case Reports in Neurology
سال: 2014
ISSN: 1662-680X
DOI: 10.1159/000369058